Clindamycin is a medicated antibiotic lotion that treats acne. Acne is a common condition that causes pimples on your skin. View clindamycin information, including dose, uses, side-effects, pregnancy, breast feeding, contra-indications, monitoring requirements and directions for administration. What is clindamycin topical? Clindamycin topical (for the skin) is used to treat severe acne in adults and children who are at least 12 years old. Clindamycin topical may also be used for purposes not listed in this medication guide. Topical clindamycin will not cure your acne. However, to help keep your acne under control, keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a few days. Topical clindamycin is commonly used to treat acne vulgaris. Acne vulgaris is a common type of acne that causes blackheads, whiteheads, and other types of pimples on your skin. Clindamycin Lotion package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology. Clindamycin (Cleocin-T) is a topical antibiotic that is used to treat mild to moderate acne. When combined with other acne medications like benzoyl peroxide or retinoids like Retin-A, it can work quite well to treat acne.